Zranb1 (基因名), Ubiquitin thioesterase Zranb1 (蛋白名), zran1_mouse.
产品名称:
Mouse Zranb1/ Ubiquitin thioesterase Zranb1 CLIA Kit
泛素thioesterase ZRANB1
货号:
U2592m
商标:
EIAab®
监管等级:
别名:
Zinc finger Ran-binding domain-containing protein 1, Trabid
检测方法:
CLIA
特异性:
Natural and recombinant mouse Ubiquitin thioesterase Zranb1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with APC and TRAF6.
功能:
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
亚细胞位置:
Cytoplasm
Nucleus
Enriched in punctate localization in the cytoplasm.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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