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ZRANB1 (基因名), Ubiquitin thioesterase ZRANB1 (蛋白名), zran1_bovin.
产品名称:

Bovine ZRANB1/ Ubiquitin thioesterase ZRANB1 ELISA Kit
泛素thioesterase ZRANB1

货号:

E2592b

商标:
EIAab®
监管等级:
别名:

Zinc finger Ran-binding domain-containing protein 1

检测方法:
ELISA
特异性:
Natural and recombinant bovine Ubiquitin thioesterase ZRANB1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine ZRANB1 ELISA Kit
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Bovine ZRANB1 ELISA Kit
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通用注释


亚单元:
Interacts with APC and TRAF6.


功能:
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.


亚细胞位置:
Cytoplasm Nucleus Enriched in punctate localization in the cytoplasm.


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