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Cebpb (基因名), CCAAT/enhancer-binding protein beta (蛋白名), cebpb_rat.
产品名称:

Rat Cebpb/ CCAAT/enhancer-binding protein beta ELISA Kit
CCAAT / enhancer-binding蛋白β

货号:

E0713r

商标:
EIAab®
监管等级:
别名:

C/EBP-related protein 2, Interleukin-6-dependent-binding protein, Liver-enriched inhibitory protein, Liver-enriched transcriptional activator, Silencer factor B, IL-6DBP, LIP, LAP, SF-B, C/EBP beta, Crp2, Nf-il6, Sfb

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.064ng/mL
特异性:
Natural and recombinant rat CCAAT/enhancer-binding protein beta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Rat Cebpb ELISA Kit
规格 & 价格: cart
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Rat Cebpb ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Binds DNA as a homodimer and as a heterodimer (PubMed:1934061). Interacts with MYB; within the complex, MYB and CEBPB bind to different promoter regions. Interacts with ATF4. Binds DNA as a heterodimer with ATF4 (By similarity). Can form stable heterodimers with CEBPA, CEBPD, CEBPE and CEBPG (PubMed:1377818, PubMed:1884998). Isoform 2 and isoform 3 also form heterodimers (PubMed:1934061). Interacts with TRIM28 and PTGES2. Interacts with PRDM16. Interacts with CCDC85B. Forms a complex with THOC5. Interacts with ZNF638; this interaction increases transcriptional activation. Interacts with CIDEA and CIDEC; these interactions increase transcriptional activation of a subset of CEBPB downstream target genes. Interacts with DDIT3/CHOP.Interacts with EP300; recruits EP300 to chromatin. Interacts with RORA; the interaction disrupts interaction with EP300. Interacts (not methylated) with MED23, MED26, SMARCA2, SMARCB1 and SMARCC1 (By similarity). Interacts with KAT2A and KAT2B (By similarity). Interacts with ATF5; EP300 is required for ATF5 and CEBPB interaction and DNA binding.


功能:
Isoform 3: Acts as a dominant negative through heterodimerization with isoform 2 (PubMed:1934061). Promotes osteoblast differentiation and osteoclastogenesis.


亚细胞位置:
Nucleus Cytoplasm Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity).


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