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Fbxo45 (基因名), F-box/SPRY domain-containing protein 1 (蛋白名), fbsp1_mouse.
产品名称:

Mouse Fbxo45/ F-box/SPRY domain-containing protein 1 ELISA Kit
含F-box/SPRY结构域蛋白

货号:

E3813m

商标:
EIAab®
监管等级:
别名:

F-box only protein 45, mFbxo45

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.098
特异性:
Natural and recombinant mouse F-box/SPRY domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Fbxo45 ELISA Kit
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Mouse Fbxo45 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Forms a complex with MYCBP2 and SKP1 but does not appear to form an authentic SCF (SKP1-CUL1-F-box protein) complex. Interacts (via B30.2/SPRY domain) with TP73 (via SAM domain); leading to its ubiquitination and degradation (By similarity). Interacts (via SRY domain) with UNC13A; leading to its degradation by the proteasome.


功能:
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Cell junction Synapse Presynaptic cell membrane


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