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JPT1 (基因名), Jupiter microtubule associated homolog 1 (蛋白名), jupi1_bovin.
产品名称:

Bovine JPT1/ Jupiter microtubule associated homolog 1 ELISA Kit

货号:

E15606b

商标:
EIAab®
监管等级:
别名:

Hematological and neurological expressed 1 protein, HN1

检测方法:
ELISA
特异性:
Natural and recombinant bovine Jupiter microtubule associated homolog 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine JPT1 ELISA Kit
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Bovine JPT1 ELISA Kit
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产品说明书
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通用注释


亚单元:
Interacts with the complex composed, at least, of APC, CTNNB1 and GSK3B; the interaction takes place with the inactive form of GSK3B (phosphorylated at 'Ser-9').


功能:
Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation.


亚细胞位置:
Nucleus Cytoplasm


该产品尚未在任何出版物中被引用。
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