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Oas3 (基因名), 2'-5'-oligoadenylate synthase 3 (蛋白名), oas3_rat.
产品名称:

Rat Oas3/ 2'-5'-oligoadenylate synthase 3 ELISA Kit
2 5 -oligoadenylate合酶3

货号:

E1715r

商标:
EIAab®
监管等级:
别名:

(2-5')oligo(A) synthase 3

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.088ng/mL
特异性:
Natural and recombinant rat 2'-5'-oligoadenylate synthase 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Immunology
Rat Oas3 ELISA Kit
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Monomer.


功能:
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。
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