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Wwox (基因名), WW domain-containing oxidoreductase (蛋白名), wwox_mouse.
产品名称:

Mouse Wwox/ WW domain-containing oxidoreductase ELISA Kit
含有氧化还原酶的WW结构域

货号:

E2982m

商标:
EIAab®
监管等级:
别名:

Wox1

检测方法:
ELISA
特异性:
Natural and recombinant mouse WW domain-containing oxidoreductase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Mouse Wwox ELISA Kit
规格 & 价格: cart
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Mouse Wwox ELISA Kit
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亚单元:
Interacts with TP53, TP73/p73 and MAPK8. Interacts with MAPT/TAU. Forms a ternary complex with TP53 and MDM2 and interacts with ERBB4, LITAF and WBP1. May interact with FAM189B and SCOTIN (By similarity). Interacts with HYAL2 and RUNX2. Interacts with TNK2 (By similarity). Interacts with TMEM207.


功能:
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development.


亚细胞位置:
Cytoplasm Nucleus Mitochondrion Partially localizes to the mitochondria (By similarity). Translocates to the nucleus in response to TGFB1 (PubMed:19366691). Translocates to the nucleus upon genotoxic stress or TNF stimulation (PubMed:11058590).


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