ACPP (基因名), Prostatic acid phosphatase (蛋白名), ppap_human.
产品名称:
ACPP Antibody
前列腺酸性磷酸
货号:
M0168Rb-h
商标:
EIAab®
监管等级:
别名:
5'-nucleotidase, Ecto-5'-nucleotidase, Thiamine monophosphatase, 5'-NT, TMPase, PAP
反应性:
human
免疫原:
Recombinant human ACPP protein ( R0168h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
应用:
推荐产品:
研究领域:
Cancer
R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
Homodimer; dimer formation is required for phosphatase activity.
功能:
Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
亚细胞位置:
Isoform 2
Cell membrane
Single-pass type I membrane protein
Lysosome membrane
Single-pass type I membrane protein
Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319).
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