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UBA3 (基因名), NEDD8-activating enzyme E1 catalytic subunit (蛋白名), uba3_human.

产品名称:

UBA3 Antibody
nedd8活化酶E1催化亚基

货号:

M1027Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-activating enzyme 3, UBE1C

反应性:

human

免疫原:

Recombinant human UBA3 protein ( R1027h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

Cancer

规格 & 价格:

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Human UBA3 Monoclonal Antibody

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R&D 技术数据

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通用注释

亚单元:

Heterodimer of UBA3 and NAE1. Interacts with NEDD8, UBE2F and UBE2M. Binds ESR1 and ESR2 with bound steroid ligand (By similarity). Interacts with TBATA.

功能:

Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

亚细胞位置:

N/A

数据库链接

UniGene:

Hs.154320

SMR:

Q8TBC4

STRING:

9606.ENSP00000354340

KEGG:

hsa:9039

MIM: