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UBR4 (基因名), E3 ubiquitin-protein ligase UBR4 (蛋白名), ubr4_human.

产品名称:

UBR4 Antibody
E3泛素连接酶UBR4

货号:

M0192Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

600 kDa retinoblastoma protein-associated factor, N-recognin-4, RING-type E3 ubiquitin transferase UBR4, Retinoblastoma-associated factor of 600 kDa, Zinc finger UBR1-type protein 1, RBAF600, KIAA0462, KIAA1307, RBAF600, ZUBR1

反应性:

human

免疫原:

Recombinant human UBR4 protein ( R0192h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Monoclonal

亚型:

Mouse IgG

应用:

推荐产品:

Goat Anti-Mouse IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human UBR4 Monoclonal Antibody

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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

通用注释

亚单元:

Interacts with RB1 and calmodulin. Interacts with protein E7 from papilloma virus HPV-16, HPV-6B and HPV-11.

功能:

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

亚细胞位置:

Membrane Multi-pass membrane protein Cytoplasm Cytoplasm Cytoskeleton Nucleus Concentrates at the leading edge of membrane structures involved in actin motility.

数据库链接

UniGene:

Hs.148078

STRING:

9606.ENSP00000364403

KEGG:

hsa:23352

MIM:

609890

Pfam:

PF13764

Uniprot:

Q5T4S7

相关产品

序列长度:

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PVETFSEFLD | VAGLLSEITD | PESFLKDLLN | SVP

3D 模型:

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验证序列:

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UBR4 AntibodyE3泛素连接酶UBR4

M0192Rb-h

600 kDa retinoblastoma protein-associated factor, N-recognin-4, RING-type E3 ubiquitin transferase UBR4, Retinoblastoma-associated factor of 600 kDa, Zinc finger UBR1-type protein 1, RBAF600, KIAA0462, KIAA1307, RBAF600, ZUBR1

UBR4 Antibody
E3泛素连接酶UBR4