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PRKAB1 (基因名), 5'-AMP-activated protein kinase subunit beta-1 (蛋白名), aakb1_human.

产品名称:

PRKAB1 Antibody

货号:

P1671Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

AMPK subunit beta-1, AMPK

序列号:

Q9Y478

反应性:

human

免疫原:

corresponding to a sequence mapping at the Recombinant protein of Q9Y478

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

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Human PRKAB1 Polyclonal Antibody

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产品说明书

数据表:

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R&D 技术数据

Immunohistochemical staining of human kidney using PRKAB1 antibody.

通用注释

亚单元:

AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.

功能:

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

亚细胞位置:

N/A

数据库链接

UniGene:

Hs.741184

SMR:

Q9Y478

STRING:

9606.ENSP00000229328

KEGG:

hsa:5564

MIM: