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IL4R (基因名), Interleukin-4 receptor subunit alpha (蛋白名), il4ra_human.
产品名称:

IL4R Antibody

货号:

P2031Rb-h

商标:
EIAab®
监管等级:
别名:

CD124, 582J2.1, IL-4 receptor subunit alpha, IL4RA

序列号:
P24394
反应性:
human
免疫原:
Recombinant human IL4R protein ( R2031h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Immunology
Human IL4R Polyclonal Antibody
规格 & 价格: cart
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Human IL4R Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry analyzes of IL4R Antibody in paraffin-embedded human breast carcinoma tissue at 1:200.
通用注释


亚单元:
The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequent recruitment to the complex of the common gamma chain, in immune cells, creates a type I receptor and, in non-immune cells, of IL13RA1 forms a type II receptor. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor (PubMed:7775445, PubMed:8804422). Interacts with PIK3C3 (By similarity). Interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP (PubMed:11714803). Interacts with JAK1 through a Box 1-containing region; inhibited by SOCS5. Interacts with SOCS5; inhibits IL4 signaling (By similarity). Interacts with JAK3 (PubMed:7538655). Interacts with CLM1.


功能:
Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.


亚细胞位置:
Isoform 2 Secreted


该产品尚未在任何出版物中被引用。
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