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KIF5A (基因名), Kinesin heavy chain isoform 5A (蛋白名), kif5a_human.
产品名称:

KIF5A Antibody

货号:

P0155Rb

商标:
EIAab®
监管等级:
别名:

Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC, NKHC1

序列号:
Q12840
反应性:
human,mouse,rat
免疫原:
Recombinant human KIF5A protein ( R0155h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human KIF5A Polyclonal Antibody
规格 & 价格: cart
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Human KIF5A Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohis tochemistry: Kinesin 5A Antibody Staining ofKIF5A in mouse brain tissue with Kif5a antibody at 5ug/ml.
通用注释


亚单元:
Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1. Interacts with FMR1 (via C-terminus); this interaction is increased in a mGluR-dependent manner. Interacts with ZFYVE27. Interacts with VAPA, VAPB, SURF4, RAB11A (GDP-bound form), RAB11B (GDP-bound form) and RTN3 in a ZFYVE27-dependent manner (By similarity). Interacts with BORCS5 (PubMed:25898167). Interacts with BICD2 (PubMed:20386726).


功能:
Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons.


亚细胞位置:
Cytoplasm Perinuclear region Cytoplasm Cytoskeleton Concentrated in the cell body of the neurons, particularly in the perinuclear region.


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