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MLANA (基因名), Melanoma antigen recognized by T-cells 1 (蛋白名), mar1_human.

产品名称:

MLANA Antibody

货号:

P1097Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A, MART-1, MART1

序列号:

Q16655

反应性:

human, mouse

免疫原:

Recombinant human MLANA Protein (R1097h)

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human MLANA Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemistry of paraffin-embedded human malignant melanoma tissue slide using MLANA Antibody at dilution of 1:150.

通用注释

亚单元:

Interacts with PMEL. Interacts with GPR143.

功能:

Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.

亚细胞位置:

Endoplasmic reticulum membrane Single-pass type III membrane protein Golgi apparatus Golgi apparatus Trans-Golgi network membrane Melanosome Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.

数据库链接

UniGene:

Hs.154069

SMR:

Q16655

STRING:

9606.ENSP00000370880

KEGG:

hsa:2315

MIM:

605513

Pfam: