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NFE2L2 (基因名), Nuclear factor erythroid 2-related factor 2 (蛋白名), nf2l2_human.
产品名称:

NFE2L2 Antibody

货号:

P3093Rb-h

商标:
EIAab®
监管等级:
别名:

HEBP1, Nuclear factor, erythroid derived 2, like 2, NF-E2-related factor 2, NRF2

序列号:
Q16236
反应性:
human
免疫原:
( )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cardiovascular
Human NFE2L2 Polyclonal Antibody
规格 & 价格: cart
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Human NFE2L2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry of paraffin-embedded human kidney cancer using NFE2L2 antibody at dilution of 1:100.
通用注释


亚单元:
Heterodimer. Forms a ternary complex with PGAM5 and KEAP1. May bind DNA with an unknown protein. Interacts via its leucine-zipper domain with the coiled-coil domain of PMF1. Interacts with EEF1D at heat shock promoter elements (HSE). Interacts (via the bZIP domain) with MAFK; required for binding to antioxidant response (ARE) elements on DNA. Interacts with CHD6; involved in activation of the transcription.


功能:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.


亚细胞位置:
Cytoplasm Cytosol Nucleus Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.


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