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SLC11A2 (基因名), Natural resistance-associated macrophage protein 2 (蛋白名), nram2_human.
产品名称:

SLC11A2 Antibody

货号:

P0316Rb

商标:
EIAab®
监管等级:
别名:

Divalent cation transporter 1, Divalent metal transporter 1, Solute carrier family 11 member 2, DMT-1, OK/SW-cl.20, NRAMP 2, DCT1, DMT1, NRAMP2

序列号:
P49281
反应性:
human,mouse,rat
免疫原:
Recombinant human SLC11A2 protein ( R0316h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human SLC11A2 Polyclonal Antibody
规格 & 价格: cart
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Human SLC11A2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of formalin-fixed and paraffin embedded rat kidney tissue using SLC11A2 antibody.
通用注释


亚单元:
Forms a complex with NDFIP1 and NEDD4L, in cortical neurons, in response to iron and colbalt exposure; this interaction leads to ubiquitination by NEDD4L and proteasome-dependent degradation. Interacts with NDFIP2. Interacts with COX2 and TOM6 at the outer mitochondrion membrane.


功能:
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.


亚细胞位置:
Endosome membrane Multi-pass membrane protein Mitochondrion outer membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


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