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OPRL1 (基因名), Nociceptin receptor (蛋白名), oprx_human.

产品名称:

OPRL1 Antibody

货号:

P9791Rb

商标:

EIAab^®

监管等级:

RUO

别名:

Kappa-type 3 opioid receptor, Orphanin FQ receptor, KOR-3, OOR, ORL1

序列号:

P41146

反应性:

human,mouse,rat

免疫原:

Recombinant human OPRL1 protein ( R9791h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human OPRL1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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通用注释

亚单元:

N/A

功能:

G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

亚细胞位置:

Cell membrane Multi-pass membrane protein Cytoplasmic vesicle Ligand binding leads to receptor internalization into cytoplasmic vesicles, decreasing the amount of available receptor at the cell surface. Internalization requires phosphorylation at Ser-363. Can recycle to the cell membrane.

数据库链接

UniGene:

Hs.2859

SMR:

P41146

STRING:

9606.ENSP00000336764

KEGG:

hsa:4987

MIM:

602548

Pfam: