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ACPP (基因名), Prostatic acid phosphatase (蛋白名), ppap_human.
产品名称:

ACPP Antibody

货号:

P0168Rb-h

商标:
EIAab®
监管等级:
别名:

5'-nucleotidase, Ecto-5'-nucleotidase, Thiamine monophosphatase, 5'-NT, TMPase, PAP

序列号:
P15309
反应性:
human
免疫原:
Recombinant human ACPP protein ( R0168h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
  • Human ACPP Polyclonal Antibody
  • Human ACPP Polyclonal Antibody
  • Human ACPP Polyclonal Antibody
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Human ACPP Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ACPP Polyclonal Antibody
MCF-7 cell linewas subjected to SDS-PAGE followed by Western Blot with Prostatic acid phosphataseantibody at dilution of 1:300
Immunoperoxidase of purified MaxPab antibody to ACPP on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml]
通用注释


亚单元:
Homodimer; dimer formation is required for phosphatase activity.


功能:
Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.


亚细胞位置:
Isoform 2 Cell membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319).


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