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SMC4 (基因名), Structural maintenance of chromosomes protein 4 (蛋白名), smc4_human.
产品名称:

SMC4 Antibody

货号:

P3349Rb-h

商标:
EIAab®
监管等级:
别名:

Chromosome-associated polypeptide C, XCAP-C homolog, hCAP-C, SMC protein 4, CAPC, SMC4L1

序列号:
Q9NTJ3
反应性:
human
免疫原:
Recombinant human SMC4 protein ( R3349h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human SMC4 Polyclonal Antibody
规格 & 价格: cart
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Human SMC4 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
Immunohistochemistry-Paraffin: SMC4 Antibody - Staining of human kidney.
通用注释


亚单元:
Forms a heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG.


功能:
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.


亚细胞位置:
Nucleus Cytoplasm Chromosome In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.


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