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ADAM17 (基因名), Disintegrin and metalloproteinase domain-containing protein 17 (蛋白名), ada17_pig.
产品名称:

Pig ADAM17/ Disintegrin and metalloproteinase domain-containing protein 17 Recombinant Protein
解整合素和金属蛋白酶结构域蛋白17

货号:

R1319p

商标:
EIAab®
监管等级:
别名:

TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM 17, TACE

序列号:
O77636
来源:
E.coli
种属:
Pig
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Pig ADAM17 Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with MAD2L1, MAPK14 and MUC1.


功能:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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