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Fbln5 (基因名), Fibulin-5 (蛋白名), fbln5_mouse.
产品名称:

Mouse Fbln5/ Fibulin-5 Recombinant Protein
HumanFIBL-5

货号:

R0209m

商标:
EIAab®
监管等级:
别名:

Developmental arteries and neural crest EGF-like protein, Dance, FIBL-5, Dance

序列号:
Q9WVH9
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Mouse Fbln5 Protein
规格 & 价格: cart
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Mouse Fbln5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer. Monomer, homodimerizes in presence of Ca(2+). Interacts with ELN (By similarity). Interacts (via N-terminus) with the integrins ITGAV/ITGB3, ITGAV/ITGB5 and ITGA9/ITGB1 (PubMed:11805835). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1.


功能:
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (By similarity). Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:11805835). May act as an adapter that mediates the interaction between FBN1 and ELN.


亚细胞位置:
Secreted Secreted Extracellular space Extracellular matrix co-localizes with ELN in elastic fibers.


该产品尚未在任何出版物中被引用。
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