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Fbxo45 (基因名), F-box/SPRY domain-containing protein 1 (蛋白名), fbsp1_mouse.
产品名称:

Mouse Fbxo45/ F-box/SPRY domain-containing protein 1 Recombinant Protein
含F-box/SPRY结构域蛋白

货号:

R3813m

商标:
EIAab®
监管等级:
别名:

F-box only protein 45, mFbxo45

序列号:
Q8K3B1
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Fbxo45 Protein
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Mouse Fbxo45 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Forms a complex with MYCBP2 and SKP1 but does not appear to form an authentic SCF (SKP1-CUL1-F-box protein) complex. Interacts (via B30.2/SPRY domain) with TP73 (via SAM domain); leading to its ubiquitination and degradation (By similarity). Interacts (via SRY domain) with UNC13A; leading to its degradation by the proteasome.


功能:
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Cell junction Synapse Presynaptic cell membrane


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