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ITM2B (基因名), Integral membrane protein 2B (蛋白名), itm2b_pig.
产品名称:

Pig ITM2B/ Integral membrane protein 2B Recombinant Protein

货号:

R2822p

商标:
EIAab®
监管等级:
别名:

Immature BRI2, Transmembrane protein BRI, imBRI2, Bri

序列号:
Q52N47
来源:
E.coli
种属:
Pig
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Pig ITM2B Protein
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with SPPL2A and SPPL2B. Interacts with APP. Mature BRI2 (mBRI2) interacts with the APP amyloid beta A4 protein; the interaction occurs at the cell surface and in the endocytic compartments and enable alpha- and beta-secretase-induced APP cleavage inhibition. Mature BRI2 (mBRI2) interacts with the APP C99; the interaction occurs in the endocytic compartments and enable gamma-secretase-induced C99 cleavage inhibition. May form heterodimers with Bri23 peptide and APP beta-amyloid protein 40.


功能:
Bri23 peptide prevents aggregation of APP beta-amyloid protein 42 peptide into toxic oligomers.


亚细胞位置:
BRI2C, soluble form Secreted


该产品尚未在任何出版物中被引用。
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