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TERF2 (基因名), Telomeric repeat-binding factor 2 (蛋白名), terf2_chick.
产品名称:

Chicken TERF2/ Telomeric repeat-binding factor 2 Recombinant Protein

货号:

R11788c

商标:
EIAab®
监管等级:
别名:

TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein, TRF2

序列号:
Q9PU53
来源:
E.coli
种属:
Chicken
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Chicken TERF2 Protein
规格 & 价格: cart
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Chicken TERF2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer. Component of the shelterin complex (telosome) (By similarity). Interacts with TERF2IP/RAP1.


功能:
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.


亚细胞位置:
Nucleus Chromosome Telomere Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.


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