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Znf423 (基因名), Zinc finger protein 423 (蛋白名), zn423_rat.
产品名称:

Rat Znf423/ Zinc finger protein 423 Recombinant Protein

货号:

R4972r

商标:
EIAab®
监管等级:
别名:

Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, rOAZ, Oaz, Zfp423

序列号:
O08961
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Znf423 Protein
规格 & 价格: cart
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Rat Znf423 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer. Interacts with PARP1, SMAD1 and SMAD4 (By similarity). Interacts with EBF1. Interacts with CEP290.


功能:
Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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