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C1QC (基因名), Complement C1q subcomponent subunit C (蛋白名), c1qc_human.
产品名称:

Human C1QC/ Complement C1q subcomponent subunit C Recombinant Protein
补体C1q子成分C亚基

货号:

R0339h

商标:
EIAab®
监管等级:
别名:

C1QG

序列号:
P02747
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human C1QC Protein
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Human C1QC Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p36.12 by HGNC 1p36.12 by Entrez Gene 1p36.12 by Ensembl
C1QC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.


功能:
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q."

[2].
"Risk of meningioma and common variation in genes related to innate immunity."

[3].
"Polymorphisms in innate immunity genes and risk of childhood leukemia."

[4].
"Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[6].
"Risk of non-Hodgkin lymphoma in association with germline variation in complement genes."

[7].
"Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met."

[8].
"Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus."

[9].
"PCR-RFLP genotyping of C1q mutations and single nucleotide polymorphisms in Malaysian patients with systemic lupus erythematosus."

[10].
"The DNA sequence and biological annotation of human chromosome 1."
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