Dog FGF1/ Heparin-binding growth factor 1 CLIA Kit
肝素结合生长因子1

货号:

U0032d

商标:

EIAab^®

监管等级:

RUO

别名:

Acidic fibroblast growth factor, Alpha-endothelial cell growth factor, Heparin-binding growth factor 1, aFGF, ECGF, HBGF-1, HBGF-1, FGF-1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

10.9-700pg/mL

特异性:

Natural and recombinant dog Heparin-binding growth factor 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Dog FGF1 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1. Interacts with S100A13.

功能:

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

亚细胞位置:

Secreted Cytoplasm Cytoplasm cell cortex Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.

数据库链接

Uniprot:

P18651