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Orai1 (基因名), Calcium release-activated calcium channel protein 1 (蛋白名), crcm1_rat.
产品名称:

Rat Orai1/ Calcium release-activated calcium channel protein 1 ELISA Kit
钙释放激活钙通道蛋白

货号:

E15347r

商标:
EIAab®
监管等级:
别名:

Protein orai-1, Transmembrane protein 142A, Cracm1, Tmem142a

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.06ng/mL
特异性:
Natural and recombinant rat Calcium release-activated calcium channel protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Rat Orai1 ELISA Kit
规格 & 价格: cart
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Rat Orai1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with STIM1 and STIM2; this regulates channel activity (By similarity). Interacts with CALM; this may displace STIM1 and STIM2 and might thereby modulate channel activity (PubMed:23109337). Interacts with CRACR2A/EFCAB4B; the interaction is direct and takes place in absence of Ca(2+) (By similarity). Forms a complex with CRACR2A/EFCAB4B and STIM1 at low concentration of Ca(2+), the complex dissociates at elevated Ca(2+) concentrations (By similarity). Interacts with SLC35G1 (By similarity). Interacts with UBQLN1.


功能:
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.


亚细胞位置:
Cell membrane Multi-pass membrane protein Cytoplasmic vesicle Autophagosome Colocalizes with UBQLN1 in the autophagosome.


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