OAS2 (基因名), 2'-5'-oligoadenylate synthase 2 (蛋白名), oas2_human.
产品名称:
OAS2 Antibody
2,5-寡腺苷酸合成酶2
货号:
M0722Rb
商标:
EIAab®
监管等级:
别名:
p69 OAS / p71 OAS, p69OAS / p71OAS, (2-5')oligo(A) synthase 2
反应性:
human, mouse
免疫原:
Recombinant human OAS2 protein ( R0722h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Monoclonal
亚型:
Mouse IgG
推荐产品:
研究领域:
Immunology
R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释
亚单元:
Homodimer.
功能:
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
亚细胞位置:
Cytoplasm
Cytoplasm
Perinuclear region
Mitochondrion
Nucleus
Microsome
Endoplasmic reticulum
Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
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