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BMP2 (基因名), Bone morphogenetic protein 2 (蛋白名), bmp2_human.
产品名称:

BMP2 Antibody

货号:

P0013Rb-h

商标:
EIAab®
监管等级:
别名:

Bone morphogenetic protein 2A, BMP-2A, BMP-2, BMP2A

序列号:
P12643
反应性:
human
免疫原:
Recombinant human BMP2 protein ( R0013h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
  • Human BMP2 Polyclonal Antibody
  • Human BMP2 Polyclonal Antibody
  • Human BMP2 Polyclonal Antibody
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Human BMP2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human BMP2 Polyclonal Antibody
Anti-BMP2 antibody IHC of human colon, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
通用注释


亚单元:
Homodimer; disulfide-linked (PubMed:10074410). Interacts with SOSTDC1 (PubMed:15020244). Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN (By similarity). Interacts with MAFP5 (By similarity). Interacts with FBN1 (via N-terminal domain) and FBN2 (PubMed:18339631).


功能:
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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